2009年2月23日星期一

Diabetic early the advantage of treatment糖尿病患者早治疗的好处

Diabetic patients the benefits of early treatment 2009-02-03 -------------------------------------------------- ------------------------------ Fasting blood glucose is not high, but after having a meal glucose rise, which belong to pre-diabetes, which should then take medicine? The past, the doctor will guide patients with lifestyle changes, such as diet, exercise and so on, but now, doctors will tell patients to change lifestyles in the meanwhile take medicine as soon as possible. Recently held in the acarbose assessment study (ACE) press conference, experts said that abnormal glucose metabolism to early intervention, with the ultimate aim is not only for lowering blood glucose, but in order to reduce cardiovascular events, namely the protection of the heart . As early as governance has three advantages According to the Chinese Medical Association Diabetes credits will be the latest epidemiological survey, China's urban residents in diabetes prevalence rate of 11%, pre-diabetes prevalence rate was 15%, that is, the community has a diabetes, there is almost a forthcoming entered the ranks of diabetes in patients with pre-diabetes. According to experts, if we do not intervene, around 1 / 3 of patients with pre-diabetes will develop diabetes. And, if only fasting glucose detection, has a significant portion of patients with abnormal glucose metabolism has been missed, especially in patients with pre-diabetes. In view of this, the United Kingdom, Oxford University Professor瓦瑞赫曼diabetes center, said the United States and Europe, 2007 "diabetes, pre-diabetes and cardiovascular diseases guidelines" recommend both fasting blood glucose tolerance test Detect and postprandial blood glucose, with a view to early detection Asymptomatic hyperglycemia and type 2 diabetes. And, as soon as possible to intervene in Europe and America has become a country doctor specialist diabetes consensus. If postprandial blood glucose control can be, there are three major advantages: First, the effective control of blood glucose and glycosylated hemoglobin, and the other is to reduce pre-diabetes progress to type 2 diabetes risk, three patients are to reduce cardiovascular risk, which is the most important of. Postprandial Hyperglycemia hurt heart A lot of patients, detection of fasting blood glucose is normal, but postprandial glucose tolerance or acceptance tests, will find significantly more than normal blood sugar, which ranged between normal and diabetes is a state of pre-diabetes, also called impaired glucose tolerance by loss. A lot of people think, not the slightly higher blood sugar you should be no harm. However, Karolinska professor at the University of Dayton Lasry pointed out that the heart of Europe and China to investigate the heart of the investigation have shown that diabetes and myocardial infarction are a lethal combination. In coronary heart disease patients, abnormal glucose metabolism (including diabetes and pre-diabetes) were generally much greater than what we imagine. "Many studies have shown that postprandial hyperglycemia and cardiovascular disease incidence and mortality are closely related." Can be seen, even if diabetes are not yet developed to the stage, the heart of pre-diabetes patients are also faced with great risks. Blood sugar began to take medicine 1 job Now that active treatment is necessary to pre-diabetes, how to use it? Acarbose is currently the only applies to pre-diabetes drugs, it is already in 27 countries were approved. There are a number of research evidence showed that acarbose treatment in patients with diabetes and other risk and incidence of myocardial infarction significantly reduced earnings are the only evidence of cardiovascular drugs Jiangtang. Acarbose security, and liver and kidney burden on small, not to increase the weight, does not produce hypoglycemia in China has been widely used and accepted.空腹血糖不高,但吃饭后血糖异常升高,这属于糖尿病前期,这种情况要不要吃药呢?过去,医生会指导患者改变生活方式,比如节食、运动等等,但如今,医生会告诉患者,在改变生活方式的同时应尽早吃药。就在前不久召开的阿卡波糖评估研究(ACE)新闻发布会上,专家表示,糖代谢异常要及早干预,其最终目的不单是为了降低血糖,而是为了减少心血管事件,即保护心脏。
  早治有三大好处
  根据中华医学会糖尿病学分会的最新流行病学调查,中国城镇居民糖尿病患病率为11%,糖尿病前期的患病率则为15%左右,即社会上有一位糖尿病患者,差不多就有一位即将步入糖尿病行列的糖尿病前期患者。据专家介绍,如果不进行干预,大约1/3的糖尿病前期患者会发展为糖尿病。
  并且,如果仅仅检测空腹血糖,有很大一部分糖代谢异常患者被漏诊,特别是糖尿病前期患者。有鉴于此,英国牛津大学糖尿病中心的瓦瑞·赫曼教授介绍说,2007美国及欧洲《糖尿病、糖尿病前期和心血管疾病指南》均推荐糖耐量试验检测空腹血糖和餐后血糖,以期尽早发现高血糖和无症状2型糖尿病。并且,尽早干预已经成为欧美国家专科糖尿病医生的共识。
  如果能将餐后血糖控制住,有三大好处:一是有效控制血糖和糖化血红蛋白,二是降低糖尿病前期进展为2型糖尿病的风险,三是减低患者的心血管风险,而这点是最重要的。
  餐后高血糖伤害心脏
  很多患者,检测空腹血糖是正常的,但餐后或接受糖耐量试验后,会发现血糖明显超过正常人,这种介于正常人和糖尿病患者之间的状态就是糖尿病前期,也叫糖耐量受损。很多人觉得,不就是血糖稍高一点吗,应该不碍事。但瑞典卡罗林斯卡大学拉斯·瑞顿教授指出,欧洲心脏调查和中国心脏调查均显示,糖尿病和心肌梗死是一对致死性组合。在冠心病患者中,糖代谢异常(包括糖尿病和糖尿病前期)远比我们想像得普遍。“很多研究表明,餐后高血糖与心血管疾病的发生率和死亡率关系密切。”可见,即便是尚未发展到糖尿病阶段,糖尿病前期病人的心脏也面临着极大的风险。
  血糖一高就开始吃药
  既然糖尿病前期就要积极治疗,该如何用药呢?阿卡波糖是目前唯一应用于糖尿病前期的药物,已经在27个国家获得批准。有多个研究证据表明,采用阿卡波糖治疗,患者的糖尿病发生风险和心肌梗死等发生率明显降低,是唯一有心血管收益证据的降糖药物。阿卡波糖安全性好,肝肾负担小,不增加体重,不产生低血糖,在中国已经得到了广泛应用和接受。

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